Skeletal Growth Imaging Lab
![Dr. Diego Jaramillo and lab members](https://www.columbiaradiology.org/sites/default/files/styles/cola_media_40_3_1/public/media/images/2021-08/group_006.jpg?itok=vgqRW0uT 40w, https://www.columbiaradiology.org/sites/default/files/styles/cola_media_200_3_1/public/media/images/2021-08/group_006.jpg?itok=EAeB4ugW 200w, https://www.columbiaradiology.org/sites/default/files/styles/cola_media_260_3_1/public/media/images/2021-08/group_006.jpg?itok=jymCYeLC 260w, https://www.columbiaradiology.org/sites/default/files/styles/cola_media_320_3_1/public/media/images/2021-08/group_006.jpg?itok=HNJ6zWEJ 320w, https://www.columbiaradiology.org/sites/default/files/styles/cola_media_400_3_1/public/media/images/2021-08/group_006.jpg?itok=5PWe-_M1 400w, https://www.columbiaradiology.org/sites/default/files/styles/cola_media_520_3_1/public/media/images/2021-08/group_006.jpg?itok=IyfpVdE5 520w, https://www.columbiaradiology.org/sites/default/files/styles/cola_media_640_3_1/public/media/images/2021-08/group_006.jpg?itok=_Rb9F6vj 640w, https://www.columbiaradiology.org/sites/default/files/styles/cola_media_800_3_1/public/media/images/2021-08/group_006.jpg?itok=TkronssY 800w, https://www.columbiaradiology.org/sites/default/files/styles/cola_media_1040_3_1/public/media/images/2021-08/group_006.jpg?itok=-3JBiEU8 1040w, https://www.columbiaradiology.org/sites/default/files/styles/cola_media_1280_3_1/public/media/images/2021-08/group_006.jpg?itok=_sUWfGjK 1280w, https://www.columbiaradiology.org/sites/default/files/styles/cola_media_1600_3_1/public/media/images/2021-08/group_006.jpg?itok=jTsvh-4L 1600w)
Skeletal Growth Imaging Lab
Location and Contact Information
The Skeletal Growth Imaging Lab is applying a novel MR technique, diffusion tensor imaging of the physis and metaphysis (DTI-P/M), to better understand normal and abnormal bone growth. We have pioneered DTI-P/M of the knee, a technique that generates tracts based on anisotropic diffusion of water through the physeal and metaphyseal columns, to measure tract volume, tract length, and fractional anisotropy (FA), a marker of tissue organization. Our central hypothesis is that height velocity, growth potential, and response to growth hormone treatment can be predicted by quantifying physeal tract volume on DTI-P/M. Our goal is to validate DTI-P/M as a biomarker for growth, with implications for assessing response to growth hormone therapy and facilitating decisions about surgical approaches to common pediatric orthopedic conditions.