Klaus A. Hamacher, PhD

Board Certifications: 
Nuclear Medicine, Diagnostic Radiology
Profile Headshot

Overview

Academic Appointments

  • Associate Professor of Radiology (Physics) at CUMC

Hospital Affiliations

  • NewYork-Presbyterian/Columbia

Languages

  • German

Gender

  • Male

Credentials & Experience

Board Certifications

  • Nuclear Medicine
  • Diagnostic Radiology

Research

Selected Publications

INVITED TALKS

• "Neutron scattering study of the magnetic properties of (1-102) Dy/Y superlattices and the intercalation of organic compounds in lipid bilayers", Los Alamos, NM, (1996).

• "The Inside Scoop of Being A Diagnostic Medical Physicist", Medical Physics Seminar, Department of Applied Physics and Mathematics, New York, NY (2012).

• "The Creative Medical Physicist: Designing Tools and Accessories for Surveys”, Medical Physics Seminar, Department of Applied Physics and Mathematics, New York, NY (2014).

TALKS

• “Intercalation of organic compounds in lipid bilayers”, MRS Fall Meeting, Boston, MA, (1994).

• “Observation of multiphoton exchange of polarized neutrons with a rapidly oscillating magnetic field using neutron interferometry”, Joint APS/AAPT Meeting, Washington, D.C., (1995).

• “Magnetic properties of (1-102) Dy/Y superlattices”, APS March Meeting, St. Louis, MO, (1996).

• “Coexistence of ferro - and helimagnetic phases in Dy/Y superlattices”, Midwest Solid State Conference, Lincoln, NE, (1996).

• “Error Analysis Of Gamma Camera Based Dosimetry In Radioimmunotherapy", Society of Nuclear Medicine Annual Meeting, Los Angeles, CA, (1999).

• “Annual Gamma Camera QC: Techniques And Phantoms To Simplify The Implementation Of The NEMA NU-1 Procedures For Tests Recommended By The ACR", American Association of Physicist in Medicine Annual Meeting, Orlando, FL, (2006).


PRESENTATIONS

• Neutron diffraction study of magnetic properties of Dy/Y superlattices. International Conference on Neutron Scattering, Toronto, Canada, (1997).

• Comparative study of the biodistribution and dosimetry of selected alpha-emitters and their daughters: a modeling analysis. Seventh Conference on Radioimmunodetection and Radioimmunotherapy of Cancer, Princeton, NJ, (1998).

• Model - derived dosimetry of selected alpha-emitters and their daughters. American Association of Physicists in Medicine Annual Meeting and Exhibition, Nashville, TN, (1999).

• Estimation Of The Immunoreactive Fraction Of Radiolabeled Antibodies: Development Of A New Mathematical Method And Comparison With Lindmo Method. Society of Nuclear Medicine Annual Meeting, Philadelphia, PA, (2004).

• Extended List Mode: Maximized Information Retention In The Days Of Cheap Memory. Society of Nuclear Medicine Annual Meeting, Philadelphia, PA, (2004).

• Annual Gamma Camera QC: Techniques And Phantoms To Simplify The Implementation Of The NEMA NU-1 Procedures For Tests Recommended By The ACR. Society of Nuclear Medicine - Regional Meeting of the Greater New York and Greater New England Chapters, Newport, RI, (2005).

• Exposure Rate Calculation: Effect Of Photon Divergence Near A Radioactive Source. Society of Nuclear Medicine - Regional Meeting of the Greater New York and Greater New England Chapters, Newport, RI, (2005).

• Performance Evaluation Of A SFOV Solid State Imaging System.  Society of Nuclear Medicine Annual Meeting, San Diego, CA, (2006).

• Exposure Rate Calculation: Effect Of Photon Divergence Near A Radioactive Source. American Association of Physicist in Medicine Annual Meeting, Orlando, FL, (2006).

PUBLICATIONS

• Kaiser H, Hamacher K, Kulasekere R,  Lee WT, Ankner JF, DeFacio B, Miceli P, Worcester DL;  Neutron inverse optics in layered materials;  SPIE; 1994; 2241; 78-89.

• Summhammer J, Hamacher KA, Kaiser H, Weinfurter H, Jacobson DL, Werner SA;  Multiphoton exchange amplitudes observed by neutron interferometry; Phys Rev Let; 1995; 75 (18); 3206-3209.

• Wagh AG, Rakhecha VC, Summhammer J, Badurek G, Weinfurter H, Allman BE, Kaiser H, Hamacher K, Jacobson DL, Werner SA ;  Neutron interferometric separation of geometric and dynamical phases;  J Phys Soc Jpn; 1996; 65 Suppl. A; 73-76.

• Summhammer J, Wagh AG, Kaiser H, Hamacher KA, Allman BE, Weinfurter H, Jacobson DL;  Photon exchange and geometric phase observed by polarized neutron interferometry;  In: DeMartini F, Denardo G, Shih Y, eds: Quantum Interferometry;  Proceedings of an Adriatico Workshop; 1996 March; Trieste.  New York: VCH Publishers Inc. 1996; 380-390.

• Theis-Bröhl K, Ritley KA, Flynn CP, Hamacher K, Kaiser H, Rhyne JJ;  Magnetic properties of (1-102)Dy/Y superlattices;  J Appl Phys; 1996; 79; 4779-4781.

• Worcester DL, Hamacher K, Kaiser H, Kulasekere R, Torbet J;  Intercalation of small hydrophobic molecules in lipid bilayers containing cholesterol;  Schoenborn and Knott eds.  Neutrons in Biology; 1996; 163; 215-226.

• Hamacher KA, Kaiser H, Kulasekere R, Worcester DL.  Intercalation of organic compounds in lipid bilayers; Mat Res Soc Symp Proc; 1995; 376; 297-299.

• Wagh AG, Rakhecha VC, Summhammer J, Badurek G, Weinfurter H, Allman BE, Kaiser H, Hamacher K, Jacobson DL, Werner SA;  Experimental separation of geometric and dynamical phases using neutron interferometery;  Phys Rev Let; 1997; 78; 755-759.

• Theis-Bröhl K, Ritley KA, Flynn CP, Van Nostrand JE, Cahill DG, Hamacher K, Kaiser H, Rhyne JJ;  Co-existing ferro- and helimagnetism in Dy/Y superlattices;  J Appl Phys; 1997; 81; 1-3.

• Theis-Bröhl K, Ritley KA, Flynn CP, Van Nostrand JE, Hamacher K, Kaiser H, Rhyne JJ.  Coexistence of different magnetic phases in Dy/Y superlattices caused by growth induced nanostructures;  J Magn Magn Mat; 1997; 166; 27-37.

• Boedeker P, Sonntag P, Schreyer A, Zabel H, Borchers J, Hamacher K, Kaiser H;  Effect of Fe cap layers on the Spin Density Waves in Epitaxial Cr(001) Films;  J Appl Phys; 1997; 81; 5247.

• Boedeker P, Sonntag P, Schreyer A, Borchers J, Hamacher K, Kaiser H;  Spin-density-waves in epitaxial Fe/Cr films;  Physica B; 1997; 464; 234-236.

• Sherman BW, Hamacher K; Power supply design in the undergraduate curriculum; IEEE Trans Educ; 1997; 40 (4); 278-282.

• Sonntag P, Boedeker P, Schreyer A, Hamacher K, Kaiser H;  Magnetic phase diagram for spin-density-waves in thin epitaxial Cr(001) films;  J Magn Magn Mat; 1998; 183; 5-18.

• Hamacher KA, Sgouros G; A schema for estimating absorbed dose to organs following the administration of radionuclides with multiple unstable daughters: A matrix approach; Med Phys; 1999; 26 (12); 2526-2528.

• Kolbert KS, Hamacher KA, Jurcic JG, Scheinberg DA , Larson SM, Sgouros G;  Parametric Images of Antibody Pharmacokinetics in Bi-213-HuM195 Therapy of Leukemia;  J Nuc Med; 2001; 42; 27-32.

• Hamacher KA, Den RB, Den EI, Sgouros G;  Cellular dose conversion factors for alpha-particle emitting radionuclides of interest in radionuclide therapy;  J Nuc Med; 2001; 42; 1216-1221.

• Ballangrud ÅM, Yang W-H, Charlton DE, McDevitt MR, Hamacher KA, Panageas KS, Ma D, Bander NH, Scheinberg DA, Sgouros G;  Response of LNCaP spheroids following treatment with alpha-particle-emitter (213Bi)-labeled anti-PSMA antibody (J591);  Can Res 2001; 61; 2008-2014.

• Hamacher KA, Sgouros G;  Theoretical estimation of absorbed dose to organs in RIT using radionuclides with multiple unstable daughters;  Med Phys; 2001; 28 (9); 1857-1874.

• Jurcic JG, Larson SM, Sgouros G, McDevitt MR, Finn RD, Divgi CR, Ballangrud AM, Hamacher KA, Ma D, Humm JL, Brechbiel MW, Molinet R, Scheinberg DA;  Targeted alpha particle immunotherapy for myeloid leukemia;  Blood; 2002; 100 (4); 1233-1239.

• Konishi S, Hamacher KA, Vallabhajosula S, Kothari P, Bastidas D, Bander NH, Goldsmith SJ; Determination of Immunoreactive Fraction of Radiolabeled Monoclonal Antibodies: What is an Appropriate Method? Cancer Biother and Radiopharmma; 2004; 19; 706-715.

• Vallabhajosula S, Kuji I, Hamacher KA, Konishi S, Kostakoglu L, Kothari PA, Milowski MI, Nanus DM, Bander NH, and Goldsmith SJ;  Pharmacokinetics and Biodistribution of 111In and 177Lu-Labeled J591 Antibody Specific for Prostate-Specific Membrane Antigen: Prediction of 90Y-J591 Radiation Dosimetry Based on 111In or 177Lu?; J Nucl Med; 2005; 46; 634-641.

• Vallabhajosula S, Goldsmith SJ, Hamacher KA, Kostakoglu L, Konishi S, Milowski MI, Nanus DM, Bander NH; Prediction of Myelotoxicity Based on Bone Marrow Radiation-Absorbed Dose: Radioimmunotherapy Studies Using 90Y- and 177Lu-Labeled J591 Antibodies Specific for Prostate-Specific Membrane Antigen; J Nucl Med; 2005; 46; 850-858.

•  Schmidtlein CR, Kirov AS, Nehmeh SA, Erdi YE, Humm JL, Amols HI, Bidaut LM, Ganin A, Stearns CW, McDaniel DL, Hamacher KA; Validation of GATE Monte Carlo simulations of the GE Advance/Discovery LS PET scanners; Med Phys; 2006; 33(1); 198-208.

• Voss HU, Uluç AM, Dyke JP, Watts R, Kobylarz EJ, McCandliss BD, Heier LA, Beattie BJ, Hamacher KA, Vallabhajosula S, Goldsmith, Ballon D, Giacino JT, Schiff ND; Possible axonal regrowth in late recovery from the minimally conscious state; J Clinical Investigation; 2006; 116(7); 2005-2011.