Christoph W Juchem, PhD

Profile Headshot

Overview

Academic Appointments

  • Associate Professor of Radiology

Dr. Christoph Juchem’s research focuses on the improvement of technology and methods to enhance the clinical potential of magnetic resonance imaging (MRI) and spectroscopy (MRS). The goal of his laboratory is to provide crucial tools to obtain information early in the development of multiple sclerosis and other neurological conditions with dedicated MRI/MRS techniques. Of particular interest to Dr. Juchem are the physical and engineering challenges that have prevented magnetic resonance technology to unleash its full clinical potential such as limited B0 field behavior in the human brain. He developed a novel, generalized method for the synthesis of magnetic field shapes that allows unrivaled B0 magnetic field homogeneity as a prerequisite for meaningful MRI and MRS. Due to the inherently interdisciplinary design of research program, Dr. Juchem works closely with a range of scientists and clinicians.

Dr. Juchem received a MS (Diplom) in physics from the University of Bonn in 2001 and a PhD (Dr. rer. nat.) in physics from the University of Tübingen, in 2006. He recently joined Columbia from Yale University where he successfully pursued clinical MRI/MRS research as Assistant Professor (2012-2016) and served as Co-Director of the 7 Tesla Brain MR Spectroscopy Core. Dr. Juchem has more than 15 years of experience in developing and conducting magnetic resonance experiments in animal models and humans, and authored more than 30 scientific publications, book chapters and patents. He is a Clinical and Translational Science Award (CTSA) scholar and has been a finalist of the I.I. Rabi Young Investigator Award of the International Society for Magnetic Resonance in Medicine (ISMRM). Dr. Juchem served as Chair of the ISMRM’s MR Engineering Study Group, journal reviewer for more than 15 peer-reviewed scientific journals (including Magnetic Resonance in Medicine Distinguished Reviewer in 2014/2016) and grant reviewer for 4 national research societies.

Magnetic Resonance Engineering for Clinical Excellence (MR SCIENCE) Laboratory:

http://juchem.bme.columbia.edu/

Languages

  • German
  • Spanish

Gender

  • Male

Credentials & Experience

Education & Training

  • MS, 2001 Physics, Rheinische Friedrich
  • PhD, 2006 Physics, Eberhard-Karls Universitat Tubingen

Honors & Awards

  • Clinical and Translational Science Award (CTSA) Scholar, YCCI, New Haven, CT, 2013
  • Finalist, Rabi Young Investigator Award, ISMRM Annual Meeting, Montreal, QC, Canada, 2011
  • Stipend of the German Scholars Organization (GSO), Berlin, Germany, 2011
  • Best scientific poster in engineering, ISMRM Annual Meeting, Stockholm, Sweden, 2010
  • Brown Coxe Postdoctoral Fellowship in the Medical Sciences, Yale University, 2007

Research

Selected Publications

  • Juchem C, Nahhass OM, Nixon TW, de Graaf RA. Multi-Slice Magnetic Resonance Imaging with the Dynamic Multi-Coil Technique. NMR Biomed 28:1526-1534 (2015).
  • Juchem C*, Umesh Rudrapatna*, Nixon TW, de Graaf RA. Dynamic Multi-Coil Technique (DYNAMITE) Shimming for Echo-Planar Imaging of the Human Brain at 7 Tesla. *contributed equally. NeuroImage 105:462-472 (2015).
  • Juchem C, Herman P, Sanganahalli BG, Nixon TW, Brown PB, McIntyre S, Hyder F, de Graaf RA. Dynamic Multi-Coil Technique (DYNAMITE) Shimmed EPI of the Rat Brain at 11.7 Tesla. NMR Biomed 27, 897-906 (2014).
  • Juchem C, Nixon TW, McIntyre S, Boer VO, Rothman DL, de Graaf RA. Dynamic Multi-Coil Shimming of the Human Brain at 7 Tesla. J Magn Reson 212, 280-288 (2011).
  • Juchem C, Brown PB, Nixon TW, McIntyre S, Rothman DL, de Graaf RA. Multi-Coil Shimming of the Mouse Brain. Magn Reson Med 66, 893-900 (2011).
  • Juchem C, Nixon TW, McIntyre S, Rothman DL, de Graaf RA. Magnetic Field Modeling with a Set of Individual Localized Coils. J Magn Reson 204, 281-289 (2010).
  • Juchem C. Passive Shimming for MR Spectroscopy at High Magnetic Fields. US Patent 7,459,908 B2 (2008)
  • Juchem C, Logothetis NK, Pfeuffer J. 1H MR Spectroscopy of the Macaque Primary Visual Cortex at 7 Tesla: Strategies and Pitfalls of Shimming at the Brain Surface. Magn Reson Imaging 25, 902-912 (2007).
  • Juchem C, Muller-Bierl B, Schick F, Logothetis NK, Pfeuffer J. Combined Passive and Active Shimming for In Vivo MR Spectroscopy at High Magnetic Fields. J Magn Reson 183, 278−289 (2006).